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Brain Shrinkage Without Reason? This Disease May Be the Answer — and It's More Common Than You Think

Binswanger's disease is a type of vascular dementia that attacks unnoticed, starting with mood changes and memory loss. It is caused by damage to small blood vessels in the brain, often associated with high blood pressure and age. Many people do not know that this disease can be treated if detected early.

27 Jun 20264 min read0 viewsBy Redaksi KhatulistiwaWikipedia — Binswanger's disease
Brain Shrinkage Without Reason? This Disease May Be the Answer — and It's More Common Than You Think
Image: Foto: Wikipedia — Binswanger's disease (CC BY-SA 4.0)
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What Exactly Is Binswanger's Disease?

Have you ever heard of a disease that silently attacks, damages memory, and changes a person's mood without warning? That is Binswanger's disease, also known in medical terms as subcortical leukoencephalopathy and subcortical arteriosclerotic encephalopathy. This disease is a type of vascular dementia that originates from damage to small blood vessels in the brain, particularly in the white matter (brain's white matter). When this white matter is damaged, it causes problems with the brain's executive functions — such as decision-making, planning, and remembering.

According to research, this disease was first identified by German neurologist Otto Binswanger in 1894. However, it was not until 1962 that Jerzy Olszewski conducted in-depth research that opened the eyes of the medical world to how serious this disease is. Although it is not as well-known as Alzheimer's, its effects are equally devastating.

How Can This Disease Occur?


Imagine your brain like a sophisticated computer. The white matter is like cables connecting all parts of the brain. When these cables are damaged due to chronic high blood pressure or aging, the signals between different parts of the brain become disrupted. Binswanger's disease usually appears between the ages of 54 and 66, but it can start earlier if the risk factors are high.

The first symptoms often reported are a gradual decline in mental ability — such as difficulty concentrating, forgetfulness, and drastic mood changes. Some people may also experience mini-strokes without realizing it. Studies show that both men and women are at risk, but those with a history of high blood pressure, diabetes, or heart disease are more vulnerable.

Early Signs That Many Overlook


What are the signs you should watch for? First, changes in short-term memory — for example, forgetting where your keys are or the name of someone you just met. Second, emotional changes such as depression, irritability, or lack of interest in activities once enjoyed. Third, movement problems — such as unstable steps, frequent falls, or slow movements.

Interestingly, many patients and their families consider these symptoms as "normal aging" and do not seek early treatment. Yet, the earlier it is detected, the greater the chance to slow down the progression of the disease. Doctors usually perform an MRI or CT scan to see changes in the brain's white matter.

Can It Be Treated?


This is the most important question. So far, there is no medicine that can completely cure Binswanger's disease. However, treatment can help manage symptoms and slow the decline. The main focus is on controlling risk factors such as high blood pressure, cholesterol, and diabetes. Doctors may prescribe anti-hypertensive drugs, statins, or anticoagulants to reduce the risk of stroke.

In addition, cognitive therapy and physical therapy can help patients maintain brain function and mobility. Family support is also very important — a calm environment and consistent daily routines can reduce confusion for the patient. Although memory may not fully recover, it can be maintained through mental exercises such as puzzles or reading.

How Long Can a Person Live With This Disease?


The life expectancy of Binswanger's disease patients varies depending on the severity and treatment. On average, patients can live between 5 to 10 years after diagnosis, but some can live longer if risk factors are well controlled. This disease is often associated with repeated strokes, which can accelerate the decline. However, with proper management, quality of life can still be improved.

It is important to remember that each patient is unique. Some experience slow progression, while others progress faster. Therefore, regular monitoring with a neurologist is essential. Do not hesitate to seek help if you or a loved one shows suspicious symptoms.

Why Are So Few People Aware of This Disease?


This may be because Binswanger's disease is rarely mentioned in mainstream media. The focus is usually on Alzheimer's or Parkinson's. However, awareness of vascular dementia is increasing among doctors. According to the Alzheimer's Association, vascular dementia accounts for 15-20% of all dementia cases, and Binswanger's is part of it.

What can we do? First, keep your blood pressure under control — manage it with a low-salt diet and light exercise. Second, do not ignore early symptoms — consult a doctor if there are significant changes in memory or mood. Third, spread this information — so more people know that this disease exists and can be treated.

This disease reminds us that the brain is a fragile organ that requires lifelong care. Don't wait until it's too late.

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Reference: Binswanger's disease — Wikipedia

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